Antisense Promoter of Human L1 Retrotransposon Drives Transcription of Adjacent Cellular Genes

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L1 Antisense Promoter Drives Tissue-Specific Transcription of Human Genes

Transcription of transposable elements interspersed in the genome is controlled by complex interactions between their regulatory elements and host factors. However, the same regulatory elements may be occasionally used for the transcription of host genes. One such example is the human L1 retrotransposon, which contains an antisense promoter (ASP) driving transcription into adjacent genes yieldi...

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ژورنال

عنوان ژورنال: Molecular and Cellular Biology

سال: 2001

ISSN: 0270-7306,1098-5549

DOI: 10.1128/mcb.21.6.1973-1985.2001